Research advances in the understanding and treatment of addiction.

  title={Research advances in the understanding and treatment of addiction.},
  author={Charles P O'brien},
  journal={The American journal on addictions},
  volume={12 s2},
The likelihood of developing an addictive disorder is a function of multiple simultaneous, pharmacologic, genetic, and environmental variables, such as the pharmacology of the drug, the route of administration, the personality of the individual, and the availability of the drug. There is increasing evidence that long-lasting changes in the brain result from the progression of casual user to addict. Moreover, the course of the progression of addiction is similar to that of other chronic diseases… CONTINUE READING

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