Research Review: Williams syndrome: a critical review of the cognitive, behavioral, and neuroanatomical phenotype.

@article{Martens2008ResearchRW,
  title={Research Review: Williams syndrome: a critical review of the cognitive, behavioral, and neuroanatomical phenotype.},
  author={Marilee Martens and Sarah J Wilson and David C. Reutens},
  journal={Journal of child psychology and psychiatry, and allied disciplines},
  year={2008},
  volume={49 6},
  pages={
          576-608
        }
}
This review critically examines the research findings which characterize the cognitive, behavioral, and neuroanatomical features of Williams syndrome (WS). This article analyzes 178 published studies in the WS literature covering the following areas: 1) General intelligence, 2) Language skills, 3) Visuospatial and face processing skills, 4) Behavior patterns and hypersociability, 5) Musical abilities, and 6) Brain structure and function. We identify methodological issues relating to small… 

Williams syndrome and its cognitive profile: the importance of eye movements.

People with Williams syndrome (WS), a rare neurodevelopmental disorder that is caused by a deletion on the long arm of chromosome 7, often show an uneven cognitive profile with participants

Williams syndrome and its cognitive profile: the importance of eye movements

Although more research on eye movements in WS is required, the importance of eye movements for cognitive development suggests a possible intervention pathway to improve cognitive abilities in this population.

Williams syndrome-specific neuroanatomical profile and its associations with behavioral features

Chapter 5 - Williams Syndrome

Social Brain Development in Williams Syndrome: The Current Status and Directions for Future Research

This article discusses how distinctive social behaviors in WS may be associated with alterations or delays in the cortical representation of faces, connectivity within the ventral stream, structure and function of the amygdala and how long- and short-range connections develop within the brain.

Variability and standardized test profiles in typically developing children and children with Williams Syndrome.

There was significantly less variability in younger WS participants for performance scores on Pattern Construction compared to the TD group, and methodological issues and the importance of taking CA into account in analyses will be discussed.

NeuroImage: Clinical Williams syndrome-speci fi c neuroanatomical pro fi le and its associations with behavioral features

The results imply that the unique behaviors in WS were mediated through the constellation of abnormalities in cortical-subcortical circuitry consistent in child WS and adult WS.

Williams syndrome: on the role of intellectual abilities in anxiety

Using ordinal logistic regression analyses, it is shown that decreasing intelligence quotient (IQ) and age are associated with elevated anxiety and low IQ was associated with higher risk of having an anxiety diagnosis.

Relationship Between Brain Abnormalities and Cognitive Profile in Williams Syndrome

Previous studies have shown inconsistent results when reporting brain abnormalities in Williams syndrome (WS). This makes an interpretation of clinical and behavioural data uncertain in terms of
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The rare, genetically based disorder, Williams syndrome (WMS), produces a constellation of distinctive cognitive, neuroanatomical, and electrophysiological features which we explore through the

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Williams syndrome (WS) is a genetic disorder resulting from a deletion on Chromosome 7. Individuals with WS exhibit distinct physical features such as facial abnormalities, hypercalcemia, and

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The special characteristics of Williams syndrome provide an opportunity to challenge and develop theories of cognition and forge links between specific neuropsychological, neuroanatomical, and genetic underpinnings relevant to developmental cognitive neuroscience.

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Compared to all other groups including the controls, the WS individuals displayed greater emotional responses to music, manifested interest in music at an earlier age, and spent more hours per week listening to music.
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