Rescuing chemotaxis of the anticancer agent Salmonella enterica serovar Typhimurium VNP20009.

Abstract

The role of chemotaxis and motility in Salmonella enterica serovar Typhimurium tumor colonization remains unclear. We determined through swim plate assays that the well-established anticancer agent S. Typhimurium VNP20009 is deficient in chemotaxis, and that this phenotype is suppressible. Through genome sequencing, we revealed that VNP20009 and four… (More)
DOI: 10.1016/j.jbiotec.2015.07.010

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