Rescue therapy for lamivudine-resistant chronic hepatitis B: comparison between entecavir 1.0 mg monotherapy, adefovir monotherapy and adefovir add-on lamivudine combination therapy.

@article{Kim2010RescueTF,
  title={Rescue therapy for lamivudine-resistant chronic hepatitis B: comparison between entecavir 1.0 mg monotherapy, adefovir monotherapy and adefovir add-on lamivudine combination therapy.},
  author={Hong Joo Kim and Jung Ho Park and Dong Il Park and Yong Kyun Cho and Chong Il Sohn and Woo Kyu Jeon and Byung Ik Kim},
  journal={Journal of gastroenterology and hepatology},
  year={2010},
  volume={25 8},
  pages={1374-80}
}
BACKGROUND AND AIM There have been no reports comparing the therapeutic results of adefovir (ADV) and entecavir (ETV) rescue therapy for patients with lamivudine (LAM)-resistant chronic hepatitis B (CHB). We aimed to compare the cumulative efficacy and resistance of ETV 1.0 mg monotherapy, ADV monotherapy and ADV add-on LAM combination therapy in LAM-refractory patients. METHODS One hundred and four patients were included in the following three treatment groups; group 1 (n = 24), LAM was… CONTINUE READING

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