Rescue Therapy for Acute Migraine, Part 1: Triptans, Dihydroergotamine, and Magnesium

@article{Kelley2012RescueTF,
  title={Rescue Therapy for Acute Migraine, Part 1: Triptans, Dihydroergotamine, and Magnesium},
  author={Nancy E. Kelley and Deborah E Tepper},
  journal={Headache: The Journal of Head and Face Pain},
  year={2012},
  volume={52}
}
Objective.— To review and analyze published reports on the acute treatment of migraine headache with triptans, dihydroergotamine (DHE), and magnesium in emergency department, urgent care, and headache clinic settings. 

Rescue Therapy for Acute Migraine, Part 3: Opioids, NSAIDs, Steroids, and Post‐Discharge Medications

Objective.— The final section of this 3‐part review analyzes published reports involving the acute treatment of migraine with opioids, non‐steroidal anti‐inflammatory drugs (NSAIDs), and steroids in

Rescue Treatment for Migraine Headache in Emergency Department Part 2: Role of Antiepileptic, Magnesium, Corticosteroids, and Discharge Care

TLDR
Nearly half of patients with migraine headaches discharged from the ED had received neither a specific diagnosis nor appropriate patient education, so discharge planning and a migraine education program at the ED was also highlighted in this article.

Intravenous Therapies for Intractable Headache

TLDR
This chapter reviews several pharmacological options of intravenous infusions for intractable headaches and recommends several new drugs for treatment of refractory headaches.

Real-world economic impact of onabotulinumtoxina in patients with chronic migraine

TLDR
OnabotulinumtoxinA can be used effectively for headache prophylaxis in CM patients with CM, but the effect of treatment on HRU is unknown.

Pharmacologic Management of Acute Migraines in the Emergency Department

TLDR
The best evidence behind some of the medications frequently used to treat acute migraines in the ED setting are reviewed, including dopamine receptor antagonists, serotonin receptor agonists, anti-inflammatory medications, opioids, magnesium, valproate, and propofol.

Acute Treatment of Migraines

TLDR
NSAIDs have both peripheral and central effects on reversing migraine, and so may represent the best alternative for patients who cannot use triptans and ergots due to vascular contraindications.

Acute Migraine Management in Children

TLDR
Development of emergency department guidelines for the management of pediatric migraines should be based on up-to-date evidence supporting safe, appropriate therapies for children, and requiring prompt nuanced recognition by emergency personnel and implementation of an effective treatment strategy.

Metoclopramide versus sumatriptan in the treatment of migraine in the emergency department: a single-center, open-label, cluster-randomized controlled non-inferiority trial.

TLDR
Whether metoclopramide 10 mg intravenously (IV) is non-inferior to sumatriptan 3 mg subcutaneously (SQ) as migraine treatment in the ED is investigated, and if this hypothesis is confirmed, metoclobramide can be considered as first-line medication for migraine attacks in ED settings.

Acute Migraine Management in Children.

TLDR
Development of emergency department guidelines for the management of pediatric migraines should be based on up-to-date evidence supporting safe, appropriate therapies for children, according to the Agency for Healthcare Research and Quality.

Migraine Treatment: Current Acute Medications and Their Potential Mechanisms of Action

TLDR
The current approach and concepts relevant to the acute pharmacological treatment of migraine will be explored in this review.
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