Requirements for the assembly and release of Newcastle disease virus-like particles.

@article{Pantua2006RequirementsFT,
  title={Requirements for the assembly and release of Newcastle disease virus-like particles.},
  author={Homer Dadios Pantua and Lori W. McGinnes and Mark E Peeples and Trudy G. Morrison},
  journal={Journal of virology},
  year={2006},
  volume={80 22},
  pages={11062-73}
}
Paramyxoviruses, such as Newcastle disease virus (NDV), assemble in and bud from plasma membranes of infected cells. To explore the role of each of the NDV structural proteins in virion assembly and release, virus-like particles (VLPs) released from avian cells expressing all possible combinations of the nucleoprotein (NP), membrane or matrix protein (M), an uncleaved fusion protein (F-K115Q), and hemagglutinin-neuraminidase (HN) protein were characterized for densities, protein content, and… CONTINUE READING

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