Requirements for stimulation of autoreactive T cells by thymic stroma.

Abstract

Thymic stromal cells are more efficient than similarly treated spleen cells for Ag presentation to Ag-specific, MHC-restricted T cell lines. Thymic stromal cells fail, however, to stimulate proliferation of autoreactive T cell lines. This failure to stimulate autoreactive T cells does not appear to be due to tolerance induction because thymic stroma does… (More)

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@article{Burstyn1989RequirementsFS, title={Requirements for stimulation of autoreactive T cells by thymic stroma.}, author={Don G. Burstyn and Marjorie G. Zauderer}, journal={Journal of immunology}, year={1989}, volume={143 5}, pages={1422-5} }