Requirement of perioperative stress doses of corticosteroids: a systematic review of the literature.

  title={Requirement of perioperative stress doses of corticosteroids: a systematic review of the literature.},
  author={Paul Ellis Marik and Joseph Varon},
  journal={Archives of surgery},
  volume={143 12},
OBJECTIVE To determine the requirement for perioperative supplemental (stress) doses of corticosteroids in patients receiving long-term corticosteroid therapy and undergoing a surgical procedure. Corticosteroids are among the most commonly prescribed medications and will predictably result in suppression of the hypothalamic-pituitary-adrenal axis with long-term use. Patients receiving therapeutic dosages of corticosteroids frequently require surgery; these patients are almost universally… CONTINUE READING


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