Requirement of nitric oxide for murine oocyte maturation, embryo development, and trophoblast outgrowth in vitro.

@article{Sengoku2001RequirementON,
  title={Requirement of nitric oxide for murine oocyte maturation, embryo development, and trophoblast outgrowth in vitro.},
  author={Kazuo Sengoku and Noriko Takuma and Michiharu Horikawa and Kanami Tsuchiya and Hiroyuki Komori and D Sharifa and Kenichi Tamate and Mutsuo Ishikawa},
  journal={Molecular reproduction and development},
  year={2001},
  volume={58 3},
  pages={262-8}
}
We investigated the extent to which NO participates in the developmental competence (oocyte maturation, fertilization and embryo development to blastocyst) using an in vitro culture system adding sodium nitroprusside (SNP), NO donor, and NOS inhibitor (N-omega-nitro-L-arginine methyl ester, L-NAME). We also assessed the effects of NO/NOS system on… CONTINUE READING