Requirement of methionine for the replication of canine distemper virus in Vero cells.

@article{Hirayama1985RequirementOM,
  title={Requirement of methionine for the replication of canine distemper virus in Vero cells.},
  author={Norio Hirayama and Megumi Senda and K. Kurata and Yasuhiro Yoshikawa and Kazuya Yamanouchi},
  journal={The Journal of general virology},
  year={1985},
  volume={66 ( Pt 1)},
  pages={
          149-57
        }
}
The replication of canine distemper virus (CDV) in Vero cells was found to require certain amino acids such as arginine, methionine and valine. The deprivation of methionine caused the most marked reduction in virus yield. In cells cultured in medium deprived of methionine, the early processes of viral replication such as adsorption, penetration and uncoating of virus occurred at normal rates, but the syntheses of viral RNA and protein were markedly reduced. The addition of S-adenosylmethionine… 
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