Requirement of MEF2A, C, and D for skeletal muscle regeneration.

@article{Liu2014RequirementOM,
  title={Requirement of MEF2A, C, and D for skeletal muscle regeneration.},
  author={Ning Liu and Benjamin R Nelson and Svetlana Bezprozvannaya and John M Shelton and James A. Richardson and Rhonda Bassel-Duby and Eric N. Olson},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2014},
  volume={111 11},
  pages={
          4109-14
        }
}
Regeneration of adult skeletal muscle following injury occurs through the activation of satellite cells, an injury-sensitive muscle stem cell population that proliferates, differentiates, and fuses with injured myofibers. Members of the myocyte enhancer factor 2 (MEF2) family of transcription factors play essential roles in muscle differentiation during embryogenesis, but their potential contributions to adult muscle regeneration have not been systematically explored. To investigate the… CONTINUE READING

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