Requirement for vasoactive amines for production of delayed-type hypersensitvity skin reactions

@article{Gershon1975RequirementFV,
  title={Requirement for vasoactive amines for production of delayed-type hypersensitvity skin reactions},
  author={Richard K. Gershon and Philip W. Askenase and Michael David Gershon},
  journal={The Journal of Experimental Medicine},
  year={1975},
  volume={142},
  pages={732 - 747}
}
The skin sites of the mouse where delayed-type hypersensitivity (DTH) reactions are most easily elicited (foot pads and ears) are particularly rich in 5-hydroxytryptamine (5-HT)-containing mast cells. Since mice are deficient in circulating basophils, which play a role in at least some DTH reactions, we investigated the possibility that the mast cells were… CONTINUE READING