Requirement for the Rac GTPase in Chlamydia trachomatis invasion of non-phagocytic cells.

@article{Carabeo2004RequirementFT,
  title={Requirement for the Rac GTPase in Chlamydia trachomatis invasion of non-phagocytic cells.},
  author={Rey A Carabeo and Scott S. Grieshaber and Aaron M. Hasenkrug and Cheryl A. Dooley and Ted Hackstadt},
  journal={Traffic},
  year={2004},
  volume={5 6},
  pages={418-25}
}
Chlamydiae are gram-negative obligate intracellular pathogens to which access to an intracellular environment is paramount to their survival and replication. To this end, chlamydiae have evolved extremely efficient means of invading nonphagocytic cells. To elucidate the host cell machinery utilized by Chlamydia trachomatis in invasion, we examined the roles of the Rho GTPase family members in the internalization of chlamydial elementary bodies. Upon binding of elementary bodies on the cell… CONTINUE READING
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