Requirement for autophagy in the long-term persistence but not initial formation of memory B cells.

@article{Chen2015RequirementFA,
  title={Requirement for autophagy in the long-term persistence but not initial formation of memory B cells.},
  author={Min Chen and Srikanth Kodali and Albert Jang and Le Kuai and Jin Wang},
  journal={Journal of immunology},
  year={2015},
  volume={194 6},
  pages={2607-15}
}
Autophagy is required for the long-term maintenance of Ag-specific memory B cells. However, whether autophagy is also important for the initial formation of memory B cells remains unclear. In this study, we show that newly generated memory B cells do not display active autophagy but are capable of forming Ab-secreting cells after rechallenge with Ags… CONTINUE READING