Requirement for HC-Pro processing during genome amplification of tobacco etch potyvirus.

@article{Kasschau1995RequirementFH,
  title={Requirement for HC-Pro processing during genome amplification of tobacco etch potyvirus.},
  author={K. D. Kasschau and James C. Carrington},
  journal={Virology},
  year={1995},
  volume={209 1},
  pages={268-73}
}
The helper component-proteinase (HC-Pro) of tobacco etch potyvirus (TEV) is a multifunctional protein with several known activities. The N-terminal region is required for aphid transmission and efficient genome amplification, the central region is required for long-distance movement in plants, and the C-terminal domain is a cysteine-type proteinase that autocatalytically cleaves between itself and the P3 protein. To investigate the requirement for HC-Pro-mediated proteolysis during viral… CONTINUE READING

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