Requiem for a heavyweight: the demise of creatine kinase-MB.

@article{Saenger2008RequiemFA,
  title={Requiem for a heavyweight: the demise of creatine kinase-MB.},
  author={Amy K Saenger and Allan S. Jaffe},
  journal={Circulation},
  year={2008},
  volume={118 21},
  pages={2200-6}
}
The development of rapid, automated, and accurate laboratory testing for creatine kinase MB (CK-MB) revolutionized the treatment of patients with acute cardiac events in the 1970s and 1980s.1 To clinicians, CK-MB values augmented a thorough history, physical, and ECG findings, and elevations rapidly became the gold standard for identifying cardiac injury.1 CK-MB allowed earlier diagnosis of acute myocardial infarction (AMI), and detection of reinfarction, and measurements could be used to… CONTINUE READING
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Effects of contemporary troponin assay sensitivity on the utility of the early markers myoglobin and CKMB isoforms in evaluating patients with possible acute myocardial infarction

  • P Kavsak, A MacRae, +5 authors AS. Jaffe
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