Repurposing the anthelmintic drug niclosamide to combat Helicobacter pylori

@inproceedings{Tharmalingam2018RepurposingTA,
  title={Repurposing the anthelmintic drug niclosamide to combat Helicobacter pylori},
  author={Nagendran Tharmalingam and Jenna Port and Dawilmer Castillo and Eleftherios Mylonakis},
  booktitle={Scientific Reports},
  year={2018}
}
There is an urgent need to discover novel antimicrobial therapies. Drug repurposing can reduce the time and cost risk associated with drug development. We report the inhibitory effects of anthelmintic drugs (niclosamide, oxyclozanide, closantel, rafoxanide) against Helicobacter pylori strain 60190 and pursued further characterization of niclosamide against… CONTINUE READING