Repurposing of drugs: An attractive pharmacological strategy for cancer therapeutics.

@article{Kirtonia2020RepurposingOD,
  title={Repurposing of drugs: An attractive pharmacological strategy for cancer therapeutics.},
  author={Anuradha Kirtonia and Kavita Gala and Stina George Fernandes and Gouri Pandya and Amit Kumar Pandey and Gautam Sethi and Ekta Khattar and Manoj Garg},
  journal={Seminars in cancer biology},
  year={2020}
}
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It is concluded that Some Central Nervous system drugs show a great potential as anti-cancer in vitro, in vivo and clinical trials through different mechanisms and pathways in different types of cancer that reveal a promising evidence for the repurposing of CNS drugs for new indications.
Systematic Repurposing Screening in Xenograft Models Identifies Approved Drugs with Novel Anti-Cancer Activity
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In-vivo testing of a broad compound collection in cancer xenograft models identified 3 drugs that displayed reproducible activity in combination with the chemotherapeutic temozolomide, suggesting drug repurposing is a relatively resource-intensive method that can identify approved medicines with a narrow margin of anti-cancer activity.
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