Repurposing Treatments to Enhance Innate Immunity. Can Statins Improve Neutrophil Functions and Clinical Outcomes in COPD?

@inproceedings{Walton2016RepurposingTT,
  title={Repurposing Treatments to Enhance Innate Immunity. Can Statins Improve Neutrophil Functions and Clinical Outcomes in COPD?},
  author={Georgia M. Walton and James A. Stockley and Diane Griffiths and Charandeep S. Sadhra and Thomas L. Purvis and Elizabeth Sapey},
  booktitle={Journal of clinical medicine},
  year={2016}
}

• Georgia M. Walton, James A. Stockley, +3 authors Elizabeth Sapey
• Published in Journal of clinical medicine 2016
• DOI:10.3390/jcm5100089

Drug classes used in the treatment of Chronic Obstructive Pulmonary Disease (COPD) have not changed for many years, and none to date have shown disease-modifying activity. Statins are used to help reduce cardiovascular risk, which is high in many patients with COPD. Their use has been associated with improvements in some respiratory manifestations of disease and reduction in all-cause mortality, with greatest reductions seen in patients with the highest inflammatory burden. The mechanism for… CONTINUE READING

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