Republished: Whipple's disease

  title={Republished: Whipple's disease},
  author={X. Pu{\'e}chal},
  journal={Postgraduate Medical Journal},
  pages={659 - 665}
  • X. Puéchal
  • Published 2013
  • Medicine
  • Postgraduate Medical Journal
  • Whipple's disease is a chronic, systemic infection caused by Tropheryma whipplei. Gene amplification, isolation and DNA sequencing of T whipplei have extended our knowledge of this pathogen, which is now recognised as a ubiquitous commensal bacterium. The spectrum of signs associated with T whipplei has now been extended beyond the classic form, which affects middle-aged men, and begins with recurrent arthritis followed several years later by digestive problems associated with other diverse… CONTINUE READING
    1 Citations


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