Reprotoxicity of gold, silver, and gold-silver alloy nanoparticles on mammalian gametes.

@article{Tiedemann2014ReprotoxicityOG,
  title={Reprotoxicity of gold, silver, and gold-silver alloy nanoparticles on mammalian gametes.},
  author={Daniela Tiedemann and Ulrike Taylor and Christoph Rehbock and Jurij Jakobi and Sabine B. Klein and Wilfried A Kues and Stephan Barcikowski and Detlef Rath},
  journal={The Analyst},
  year={2014},
  volume={139 5},
  pages={931-42}
}
Metal and alloy nanoparticles are increasingly developed for biomedical applications, while a firm understanding of their biocompatibility is still missing. Various properties have been reported to influence the toxic potential of nanoparticles. This study aimed to assess the impact of nanoparticle size, surface ligands and chemical composition of gold, silver or gold-silver alloy nanoparticles on mammalian gametes. An in vitro assay for porcine gametes was developed, since these are delicate… CONTINUE READING

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