Reprogramming of the immune system during zinc deficiency.

@article{Fraker2004ReprogrammingOT,
  title={Reprogramming of the immune system during zinc deficiency.},
  author={Pamela J. Fraker and Louis E. King},
  journal={Annual review of nutrition},
  year={2004},
  volume={24},
  pages={277-98}
}
Thymic atrophy, lymphopenia, and compromised cell- and antibody-mediated responses that cause increased rates of infections of longer duration are the immunological hallmarks of zinc deficiency (ZD) in humans and higher animals. As the deficiency advances, a reprogramming of the immune system occurs, beginning with the activation of the stress axis and chronic production of glucocorticoids that accelerate apoptosis among pre-B and -T cells. This reduces lymphopoiesis and causes atrophy of the… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 112 extracted citations

The immune system and the impact of zinc during aging

Immunity & Ageing • 2009
View 4 Excerpts
Highly Influenced

Practical Aspects of Hair Transplantation in Asians

Springer Japan • 2018
View 6 Excerpts
Highly Influenced

Zinc signals and immune function.

BioFactors • 2014
View 6 Excerpts
Highly Influenced

Zinc in innate and adaptive tumor immunity

Journal of Translational Medicine • 2010
View 4 Excerpts
Highly Influenced

Regulation of Dendritic Cell Function by Nutrients

EBERHARD KARLS, NguyenThi Xuan, F. Götz, Florian Lang
2009
View 4 Excerpts
Highly Influenced

Zinc in human health: effect of zinc on immune cells.

Molecular medicine • 2008
View 3 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…