Reprogramming cell fate to pluripotency: the decision-making signalling pathways.


Pluripotency can be defined as the ability of individual cells to initiate all of the lineages of the mature organism in response to signals from the environment. It has long been assumed that during development, pluripotency is progressively and irreversibly lost through a mechanism that requires strict coordination of the signalling pathways involved in… (More)
DOI: 10.1387/ijdb.103190ds


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