Reproductive toxicology profile of emtricitabine in mice and rabbits.

Abstract

Reproductive and developmental toxicology studies were conducted with emtricitabine, a nucleoside analog in development for treatment of human immunodeficiency virus (HIV) (Phase III) and hepatitis B (HBV) (Phase III) infections. Oral doses up to 1000 mg/kg/day provided daily area under the curve (AUC(0-->24)) exposure to pregnant animals approximately 60… (More)

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@article{Szczech2003ReproductiveTP, title={Reproductive toxicology profile of emtricitabine in mice and rabbits.}, author={George M Szczech and Laurene H Wang and John P. Walsh and Franck Rousseau}, journal={Reproductive toxicology}, year={2003}, volume={17 1}, pages={95-108} }