Reproductive steroid hormones and recurrence-free survival in women with a history of breast cancer.

@article{Rock2008ReproductiveSH,
  title={Reproductive steroid hormones and recurrence-free survival in women with a history of breast cancer.},
  author={Cheryl L Rock and Shirley W. Flatt and Gail A. Laughlin and Ellen B. Gold and Cynthia A Thomson and Loki Natarajan and Lovell A Jones and Bette Jane Caan and Marcia L. Stefanick and Richard Hajek and Wael K. Al-Delaimy and Frank Z. Stanczyk and John P Pierce},
  journal={Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology},
  year={2008},
  volume={17 3},
  pages={614-20}
}
Epidemiologic studies fairly consistently show in postmenopausal women that reproductive steroid hormones contribute to primary breast cancer risk, and this association is strongly supported by experimental studies using laboratory animals and model systems. Evidence linking sex hormone concentrations with risk for recurrence in women diagnosed with breast cancer is limited; however, beneficial effects of antiestrogenic therapy on recurrence-free survival suggest that these hormones affect… CONTINUE READING
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