Reproductive outcome after chromosome analysis in couples with two or more miscarriages: index [corrected]-control study.

@article{Franssen2006ReproductiveOA,
  title={Reproductive outcome after chromosome analysis in couples with two or more miscarriages: index [corrected]-control study.},
  author={Maureen T M Franssen and Johanna C. Korevaar and Fulco van der Veen and Nico J. Leschot and Patrick M. M. Bossuyt and Mariette Goddijn},
  journal={BMJ},
  year={2006},
  volume={332 7544},
  pages={759-63}
}
OBJECTIVE To compare reproductive outcomes in couples carrying a structural chromosome abnormality and non-carrier couples referred for chromosome analysis after two or more miscarriages. DESIGN Index [corrected]-control study. SETTING Six centres for clinical genetics in the Netherlands. PARTICIPANTS 278 carrier couples and 427 non-carrier couples referred for chromosome analysis between 1992 and 2000 after two or more miscarriages before 20 weeks of gestation. Couples were followed up… CONTINUE READING
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