Reproductive disorders in pubertal and adult phase of the male rats exposed to vinclozolin during puberty.

@article{Yu2004ReproductiveDI,
  title={Reproductive disorders in pubertal and adult phase of the male rats exposed to vinclozolin during puberty.},
  author={Wook Joon Yu and Beom jun Lee and Sang Yoon Nam and Byeongwoo Ahn and Jin Tae Hong and Jae Cheul Do and Young Cheul Kim and Yong Soon Lee and Young Won Yun},
  journal={The Journal of veterinary medical science},
  year={2004},
  volume={66 7},
  pages={847-53}
}
Vinclozolin (VCZ) is a systemic dicarboximide fungicide with antiandrogenic activity. Reproductive toxicity of VCZ was investigated in male rats exposed to VCZ during puberty. Sprague-Dawley male rats aged with 35 days were assigned to six different groups; negative control, positive control receiving flutamide (100 mg/kg), VCZ (100, 200 and 400 mg/kg), and a combination of VCZ (200 mg/kg) + methyltestosterone (100 mg/kg). The animals were treated with test compounds by oral gavage daily during… CONTINUE READING

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