Reproductive behavior and health in consanguineous marriages

@article{Bittles1991ReproductiveBA,
  title={Reproductive behavior and health in consanguineous marriages},
  author={A. Bittles and W. Mason and J. Greene and N. Rao},
  journal={Science},
  year={1991},
  volume={252},
  pages={789 - 794}
}
In many regions of Asia and Africa, consanguineous marriages currently account for approximately 20 to 50% of all unions, and preliminary observations indicate that migrants from these areas continue to contract marriages with close relatives when resident in North America and Western Europe. Consanguinity is associated with increased gross fertility, due at least in part to younger maternal age at first livebirth. Morbidity and mortality also may be elevated, resulting in comparable numbers of… Expand
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The recent Pakistan Demographic and Health Survey (PDHS) shows that 63 per cent of all marriages in Pakistan are consanguineous, an overwhelming majority of them being marriages between firstExpand
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References

SHOWING 1-10 OF 101 REFERENCES
Consanguineous marriage and reproduction in Beirut, Lebanon.
  • M. Khlat
  • Medicine
  • American journal of human genetics
  • 1988
TLDR
Effects of consanguineous marriages on couples' fertility and on offspring mortality were investigated in Beirut through a population-based health survey of 2,752 households, and the issue of confounding is discussed. Expand
Consanguinity, spousal age at marriage and fertility in seven Pakistani Punjab cities.
A retrospective study was conducted on spousal age at marriage, time to first birth and total pregnancies in the populations of seven cities in the Pakistani province of Punjab. ConsanguineousExpand
Consanguineous Marriage and Postnatal Mortality in Karnataka, South India
TLDR
Analysis of data on postnatal death failed to reveal a consistent, statistically significant trend with increasing consanguinity, and the probable explanation(s) for this finding and the general effects of inbreeding on the south Indian gene pool are considered. Expand
Trends in human reproductive wastage in relation to long‐term practice of inbreeding
TLDR
Taking into consideration the various socio-demographic factors, the narrowing differentials in the reproductive wastage between consanguineous and non-consanguineously marriages from the oldest to the youngest women confirm the tapering effects of continued inbreeding practices on the reproductive Wastage. Expand
Consanguineous marriages and the genetic load due to lethal genes in Kerala
TLDR
During the present study, several hospital populations in Kerala were examined for the relative mortality and morbidity of offspring from the two types of marriages and the method developed by Morton et al. (1956) for the estimation of genetic load was used for analysing the data on mortality. Expand
Consanguinity, twinning and secondary sex ratio in the population of Karnataka, south India.
TLDR
The results indicate that consanguinity is not associated with excess antenatal losses and suggest the possibility of enhanced selection against mutations at X chromosome loci. Expand
The effect of consanguineous marriages on reproductive wastage
TLDR
No consistent increase in reproductive wastage was evident as the inbreeding coefficient, F, advances mainly because of decline in the wastage rate among the double first cousin marriages which represents only 2% of the sample. Expand
Perception of consanguineous marriages and their genetic effects among a sample of couples from Beirut.
TLDR
In general, the women in consanguineous marriages were more favorably inclined than the matched women to marriages between relatives; however, about half of each group would advise their son/daughter to marry his/her cousin. Expand
Consanguineous marriage among rural Arabs in Israel.
TLDR
The prevalence of consanguineous marriages was examined among the Arab rural population in the Western Galilee region in Israel, and the most common type was first-cousin marriages, especially where the husband's father and the wife's father were brothers. Expand
Inbreeding and the incidence of childhood genetic disorders in Karnataka, South India.
TLDR
The results suggest that long term inbreeding may not have resulted in appreciable elimination of recessive lethals and sub-lethals from the gene pool. Expand
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5
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