Reproductive aging in men.

  title={Reproductive aging in men.},
  author={Shehzad S Basaria},
  journal={Endocrinology and metabolism clinics of North America},
  volume={42 2},
Aging in men is associated with a decrease in serum testosterone levels due to attrition in testicular Leydig cells and slowing of the hypothalamic GnRH pulse generator. The practicing endocrinologist is frequently consulted for consideration of testosterone therapy in older men with late-onset hypogonadism (LOH), a condition that many clinicians fail to distinguish from organic hypogonadism. Recent data using syndromic definition show that only 2% of 40-80-year-old men have LOH. Co-morbidities… CONTINUE READING
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