Reproductive Decision-Making in Women with BRCA1/2 Mutations

@article{Chan2016ReproductiveDI,
  title={Reproductive Decision-Making in Women with BRCA1/2 Mutations},
  author={Jessica Pui Lan Chan and Lauren N. C. Johnson and Mary D. Sammel and Laura M Digiovanni and Chan Voong and Susan Domchek and Clarisa R. Gracia},
  journal={Journal of Genetic Counseling},
  year={2016},
  volume={26},
  pages={594-603}
}
Expanded genetic testing of BRCA mutations has led to identification of more reproductive-aged women who test positive for the mutation which might impact attitudes and decisions about relationships, childbearing and the use of preimplantation genetic diagnosis (PGD) and prenatal diagnosis (PND). A cross-sectional survey was administered to 1081 self-reported BRCA carriers to investigate how knowledge of BRCA status influences these issues. The mean age at BRCA test disclosure was 44 years and… CONTINUE READING
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