Reproductive, menstrual, and other hormone‐related factors and risk of renal cell cancer

@article{Zucchetto2008ReproductiveMA,
  title={Reproductive, menstrual, and other hormone‐related factors and risk of renal cell cancer},
  author={Antonella Zucchetto and Renato Talamini and Luigino Dal Maso and Eva Negri and Jerry Polesel and Valerio Ramazzotti and Maurizio Montella and Vincenzo Canzonieri and Diego Serraino and Carlo la Vecchia and Silvia Franceschi},
  journal={International Journal of Cancer},
  year={2008},
  volume={123}
}
A role of hormone‐related factors in renal cell cancer (RCC) etiology has been hypothesized, but the epidemiological evidence is inconsistent. The present study aimed at evaluating the effect of reproductive, menstrual and other gender‐specific variables on RCC risk among women. This study is part of a larger hospital‐based, case‐control study on RCC risk, conducted in northern, central and southern Italy. Cases were 273 women, below age 80, with histologically confirmed, incident RCC. Controls… Expand
Menstrual and Reproductive Factors and Risk of Renal Cell Cancer in the Multiethnic Cohort
TLDR
The hypothesis that hormone-related factors play an etiologic role in RCC among women is not supported and there is no evidence of association between RCC and parity, age at first birth,Age at menarche, age and type of menopause, use and duration of oral contraceptive, and type andduration of postmenopausal hormone use. Expand
Reproductive factors and risk of renal cell cancer: the Nurses' Health Study.
TLDR
No clear associations were observed for postmenopausal hormone use or duration, time since last PMH use, oral contraceptive use orduration, age at menarche, Age at menopause, or history of hysterectomy or oophorectomy. Expand
Contribution Reproductive Factors and Risk of Renal Cell Cancer The Nurses ’ Health Study
Few prospective studies have examined associations between reproductive factors and risk of renal cell cancer (RCC). The authors prospectively examined whether postmenopausal hormone (PMH) use, oralExpand
A case–control study of reproductive factors and renal cell carcinoma among black and white women in the United States
TLDR
The findings further support an association between late maternal age at first birth and reduced RCC risk, and suggest that the association may be particularly strong for clear cell adenocarcinoma. Expand
Hysterectomy, Oophorectomy, and Risk of Renal Cell Carcinoma
TLDR
In this large prospective study, it was showed that women with a history of hysterectomy had 28% increased risk of RCC, and this finding was not modified by exogenous hormone use. Expand
Reproductive factors and kidney cancer risk in 2 US cohort studies, 1993-2010.
TLDR
It is suggested that hysterectomy is associated with increased risk of kidney cancer and the observed associations with age at menarche and oral contraceptive use warrant further investigation. Expand
Epidemiologic characteristics and risk factors for renal cell cancer
TLDR
Novel epidemiologic approaches, including evaluation of gene–environment interactions and epigenetic mechanisms of inherited and acquired increased risk, are needed to explain the increasing incidence of renal cell cancer. Expand
Epidemiology of Renal Cell Carcinoma
TLDR
The multifactorial nature of renal cell cancer requires that further studies are conducted to explain underlying factors that may influence individual risk and to elucidate complex relationships between potential genetic, lifestyle, and environmental elements on cancer development. Expand
The Relationship Between Hormone Replacement Therapy and Risk of Kidney Cancer in Women: A Meta-Analysis
TLDR
It was showed that HRT use is inversely associated with kidney cancer risk in a dose–dependent fashion and no evidence of publication bias was found. Expand
Reproductive Pattern of Parous Women and the Risk of Cancer in Later Life
TLDR
Older age at first pregnancy was associated with increased risk of breast and gastrointestinal cancer, and reduced risk of invasive cervical, carcinoma in situ of the cervix and respiratory cancer, in fertile women living in northeast Scotland. Expand
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References

SHOWING 1-10 OF 33 REFERENCES
International renal‐cell cancer study. V. Reproductive factors, gynecologic operations and exogenous hormones
TLDR
The results indicate that certain hormonal and reproductive variables may be related to risk of renal‐cell cancer and deserve further investigation, both epidemiologically and experimentally. Expand
Reproductive factors and the risk of renal cell cancer among women
TLDR
Risk of renal cell cancer associated with reproductive factors and use of oral contraceptives and menopausal hormones was positively associated with number of births and inversely associated with age at first birth, with the largest increases in risk among women with 5 or more births after age 25. Expand
Increased risk of renal cell carcinoma subsequent to hysterectomy.
TLDR
It is conjecture that unintentional injury to the ureter during the surgical procedure, which results in renal cell damage and consequent renal cell proliferation, may be a cause of the increased cancer risk in hysterectomized women. Expand
A cohort study of reproductive and hormonal factors and renal cell cancer risk in women
TLDR
Evidence is provided that high parity may beassociated with increased risk of renal cell cancer, and that oral contraceptive use may be associated with reduced risk. Expand
Renal cell cancer and body size at different ages: an Italian multicenter case-control study.
TLDR
RCC risks among overweight and obese persons were apparently higher in never smokers, persons with the clear-cell histologic type, and persons with a Fuhrman nuclear grade of G3-G4. Expand
Pregnancy and risk of renal cell cancer: a population-based study in Sweden
TLDR
The observed positive association between parity and renal cell cancer risk is unlikely to be fully explained by uncontrolled confounding, but warrants further evaluation in large studies, with allowance for body mass index. Expand
Risk factors for renal‐cell carcinoma in Denmark. III. Role of weight, physical activity and reproductive factors
TLDR
A population‐based case‐control study of risk factors for renal‐cell carcinoma in Denmark found some evidence for an association with reproductive variables, including decreased risk for women with late menarche and first pregnancy and birth and no association with number of pregnancies or age at menopause. Expand
History of treated hypertension and diabetes mellitus and risk of renal cell cancer.
TLDR
An Italian multicenter case-control study finds a possible causal role of hypertension in renal cell carcinogenesis is supported by the consistency of the direct association. Expand
Renal cell carcinoma in relation to cigarette smoking: Meta‐analysis of 24 studies
TLDR
Inhaled tobacco smoke is clearly implicated in the etiology of RCC, with a strong dose‐dependent increase in risk associated with numbers of cigarettes smoked per day and a substantial reduction in risk for long‐term former smokers. Expand
Reproductive characteristics and risk of kidney cancer: Iowa Women's Health Study.
TLDR
This study indicates that a greater exposure to estrogens may increase risk for kidney cancer, and identifies independent risk factors related to female reproductive history and its effects on development of kidney cancer. Expand
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