Reproduction of menstrual changes in transplanted human endometrial tissue in immunodeficient mice.

@article{MatsuuraSawada2005ReproductionOM,
  title={Reproduction of menstrual changes in transplanted human endometrial tissue in immunodeficient mice.},
  author={Rui Matsuura-Sawada and Takashi Murakami and Yuka Ozawa and Hiroshi Nabeshima and Jun-ichi Akahira and Yumi Sato and Yoshio Koyanagi and Mamoru Ito and Yukihiro Terada and Kunihiro Okamura},
  journal={Human reproduction},
  year={2005},
  volume={20 6},
  pages={
          1477-84
        }
}
BACKGROUND Cultures of human endometrial tissue are useful for analysing the mechanisms underlying the menstrual cycle. However, long-term culture of endometrial tissue is difficult in vitro. Xenotransplantation of normal human endometrial tissue into immunodeficient mice could allow prolonged survival of the transplanted tissues. METHODS Proliferative-phase endometrial tissue samples from three women were transplanted into the subcutaneous space of ovariectomized, immunodeficient, non-obese… CONTINUE READING

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