Reproduction impairment following paternal genotoxin exposure in brown trout (Salmo trutta) and Arctic charr (Salvelinus alpinus).

@article{Devaux2011ReproductionIF,
  title={Reproduction impairment following paternal genotoxin exposure in brown trout (Salmo trutta) and Arctic charr (Salvelinus alpinus).},
  author={Alain Devaux and Luc Fiat and Christian Gillet and Sylvie Bony},
  journal={Aquatic toxicology},
  year={2011},
  volume={101 2},
  pages={405-11}
}
This work describes some consequences of paternal germ cell DNA damage on the reproduction success in two fish species. Male brown trout (n=31) and male Arctic charr (n=28) were exposed to the model genotoxicant MMS at the end of spermatogenesis to generate a significant DNA damage level in mature spermatozoa (28% and 25% tail DNA in trout and charr sperm, respectively, evaluated through the comet assay). Sperm from each MMS exposed and control fish was then used to fertilize in vitro an… CONTINUE READING