Reproducible Automated Phosphopeptide Enrichment Using Magnetic TiO2 and Ti-IMAC

Abstract

Reproducible, comprehensive phosphopeptide enrichment is essential for studying phosphorylation-regulated processes. Here, we describe the application of hyper-porous magnetic TiO2 and Ti-IMAC microspheres for uniform automated phosphopeptide enrichment. Combining magnetic microspheres with a magnetic particle-handling robot enables rapid (45 min… (More)
DOI: 10.1021/ac5025842

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