Reproducibility of histologic classification in nonfibrotic myeloproliferative neoplasia.

  title={Reproducibility of histologic classification in nonfibrotic myeloproliferative neoplasia.},
  author={Suzanne M. Koopmans and Freek J Bot and King Hong Lam and Arienne M W van Marion and Hendrik de Raeve and Konnie M. Hebeda},
  journal={American journal of clinical pathology},
  volume={136 4},
Early phases of polycythemia vera, essential thrombocythemia, and primary myelofibrosis (PMF) can be difficult to distinguish by morphologic studies alone because they share many morphologic characteristics. Histologic criteria according to the 2008 World Health Organization (WHO) classification are part of the myeloproliferative neoplasia (MPN) diagnosis. Our aim was to assess the reproducibility of morphologic characteristics and determine their relative importance for histologic diagnoses on… CONTINUE READING


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