Reproducibility of glucose, fatty acid and VLDL kinetics and multi-organ insulin sensitivity in obese subjects with non-alcoholic fatty liver disease
@article{Magkos2011ReproducibilityOG,
title={Reproducibility of glucose, fatty acid and VLDL kinetics and multi-organ insulin sensitivity in obese subjects with non-alcoholic fatty liver disease},
author={Faidon Magkos and Elisa Fabbrini and Kevin M. Korenblat and Adewole L Okunade and Bruce W. Patterson and S. Klein},
journal={International Journal of Obesity},
year={2011},
volume={35},
pages={1233-1240}
}
Objective:Non-alcoholic fatty liver disease (NAFLD) is associated with abnormalities in basal glucose and free fatty acid (FFA) metabolism, multi-organ insulin resistance and alterations in lipoprotein kinetics. These metabolic outcomes can be evaluated in vivo by using stable isotopically labeled tracer methods. An understanding of the reproducibility of these measures is necessary to ensure adequate statistical power in studies designed to evaluate metabolic function in subjects with NAFLD… CONTINUE READING