Reproducibility of Contrast-Enhanced Ultrasound in Mice with Controlled Injection

@article{Dizeux2016ReproducibilityOC,
  title={Reproducibility of Contrast-Enhanced Ultrasound in Mice with Controlled Injection},
  author={Alexandre Dizeux and Thomas Payen and Guillaume Barrois and Delphine Le Guillou Buffello and Sharon Lori Bridal},
  journal={Molecular Imaging and Biology},
  year={2016},
  volume={18},
  pages={651-658}
}
Sensitivity of contrast-enhanced ultrasound (CEUS) to microvascular flow modifications can be limited by intra-injection variability (injected dose, rate, volume). To evaluate the effect of injection variability on microvascular flow evaluation, CEUS was compared between controlled and manual injections where enhancement was assessed in vitro within a flow phantom, in normal murine kidney (N = 12) and in murine ectopic tumors (N = 10). For both in vitro and in vivo measurements in the renal… CONTINUE READING
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