Reproducibility, and age, body-weight and gender dependency of candidate skeletal muscle MRI outcome measures in healthy volunteers

@inproceedings{Morrow2014ReproducibilityAA,
  title={Reproducibility, and age, body-weight and gender dependency of candidate skeletal muscle MRI outcome measures in healthy volunteers},
  author={Jasper M. Morrow and Christopher D. J. Sinclair and Arne Fischmann and Mary M Reilly and Michael G. Hanna and Tarek Yousry and John S. Thornton},
  booktitle={European Radiology},
  year={2014}
}
ObjectivesQuantitative magnetic resonance imaging (MRI) can potentially meet the pressing need for objective, sensitive, reproducible outcome measures in neuromuscular disease trials. We tested, in healthy volunteers, the consistency, reliability and sensitivity to normal inter-subject variation of MRI methods targeted to lower limb muscle pathology to inform the design of practical but comprehensive MRI outcome measure protocols for use in imminent patient studies.MethodsForty-seven healthy… CONTINUE READING

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