Reprint of "The developing oligodendrocyte: key cellular target in brain injury in the premature infant".

@article{Volpe2011ReprintO,
  title={Reprint of "The developing oligodendrocyte: key cellular target in brain injury in the premature infant".},
  author={Joseph J. Volpe and Hannah C. Kinney and Frances E. Jensen and Paul B Rosenberg},
  journal={International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience},
  year={2011},
  volume={29 6},
  pages={565-82}
}
Brain injury in the premature infant, a problem of enormous importance, is associated with a high risk of neurodevelopmental disability. The major type of injury involves cerebral white matter and the principal cellular target is the developing oligodendrocyte. The specific phase of the oligodendroglial lineage affected has been defined from study of both human brain and experimental models. This premyelinating cell (pre-OL) is vulnerable because of a series of maturation-dependent events. The… CONTINUE READING
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