Repression of the IL-6 gene is associated with hypermethylation.

@article{Armenante1999RepressionOT,
  title={Repression of the IL-6 gene is associated with hypermethylation.},
  author={Franca Armenante and Marcello Merola and Alberto Furia and Marta Palmieri},
  journal={Biochemical and biophysical research communications},
  year={1999},
  volume={258 3},
  pages={
          644-7
        }
}
The expression of the IL-6 gene is usually tightly controlled and may be induced in specific tissues after treatment with appropriate stimuli. Although much is known about the inducible expression of the IL-6 gene, the molecular mechanisms responsible for its repression in specific tissues or cell types remain poorly defined. To address this question we have studied two human breast carcinoma cell lines, MDA-MB-231, in which the IL-6 gene is expressed, and, MCF-7, in which the IL-6 message is… CONTINUE READING

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