Repression of osteocyte Wnt/β-catenin signaling is an early event in the progression of renal osteodystrophy.

Abstract

Chronic kidney disease-mineral bone disorder (CKD-MBD) is defined by abnormalities in mineral and hormone metabolism, bone histomorphometric changes, and/or the presence of soft-tissue calcification. Emerging evidence suggests that features of CKD-MBD may occur early in disease progression and are associated with changes in osteocyte function. To identify… (More)
DOI: 10.1002/jbmr.1630

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