Repression of antibiotic downregulator WblA by AdpA in Streptomyces coelicolor.

@article{Lee2013RepressionOA,
  title={Repression of antibiotic downregulator WblA by AdpA in Streptomyces coelicolor.},
  author={Han-Na Lee and Jin-Su Kim and Pil Kim and Heung-Shick Lee and Eung-Soo Kim},
  journal={Applied and environmental microbiology},
  year={2013},
  volume={79 13},
  pages={
          4159-63
        }
}
The upstream region of antibiotic downregulatory wblA in Streptomyces coelicolor was found to contain AdpA binding motifs. A key morphological regulator, AdpA was shown to specifically bind these motifs by electrophoretic mobility shift assay. An adpA disruption mutant exhibited increased wblA transcription, suggesting that AdpA negatively regulates wblA transcription in S. coelicolor. 

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References

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Signalling early developmental events in two highly diverged Streptomyces species.

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HIGHLY INFLUENTIAL