Repression of TFII-I-dependent transcription by nuclear exclusion.

  title={Repression of TFII-I-dependent transcription by nuclear exclusion.},
  author={Mar{\'i}a Isabel Tussi{\'e}-Luna and Dashzeveg Bayarsaihan and Frank H. Ruddle and Ananda L Roy},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={98 14},
TFII-I is an unusual transcription factor possessing both basal and signal-induced transcriptional functions. Here we report the characterization of a TFII-I-related factor (MusTRD1/BEN) that regulates transcriptional functions of TFII-I by controlling its nuclear residency. MusTRD1/BEN has five or six direct repeats, each containing helix--loop--helix motifs, and, thus, belongs to the TFII-I family of transcription factors. TFII-I and MusTRD1/BEN, when expressed individually, show predominant… CONTINUE READING
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Publications referenced by this paper.


  • Y. Franke, R. J. Peoples, U. Francke
  • Cell Genet .
  • 1999

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