Repression of Ca 2 / Calmodulin-dependent Protein Kinase IV Signaling Accelerates Retinoic Acid-induced Differentiation of Human Neuroblastoma Cells *

@inproceedings{Feliciano2009RepressionOC,
  title={Repression of Ca 2 / Calmodulin-dependent Protein Kinase IV Signaling Accelerates Retinoic Acid-induced Differentiation of Human Neuroblastoma Cells *},
  author={David M. Feliciano and Arthur M. Edelman},
  year={2009}
}
Neuroblastoma cells having stem cell-like qualities are widely employed models for the study of neural stem/progenitor cell proliferation and differentiation. We find that human BE(2)C neuroblastoma cells possess a signaling cascade initiated by Ca2 influx via voltage-dependent calcium channels and the N-methyl-D-aspartate (NMDA) receptor and culminating in nuclear calmodulin-dependent protein kinase IV (CaMKIV)mediated phosphorylation and activation of the transcription factors Ca2 /cyclic AMP… CONTINUE READING

References

Publications referenced by this paper.
Showing 1-2 of 2 references

Repression of CaMKIV Accelerates Neuronal Differentiation 26480 JOURNAL OF BIOLOGICAL CHEMISTRY VOLUME

N. D. Lawson, M. Zain, +3 authors N. Berliner
Exp. Hematol. 27, • 1999
View 14 Excerpts
Highly Influenced

C1029–C1037 Repression of CaMKIV Accelerates Neuronal Differentiation

C. C. Sucharov, S. Langer, M. Bristow, L. Leinwand
Am. J. Physiol. Cell Physiol • 2006

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