Repression by SSN 6 - TUP 1 is directed by MIG 1 , a repressor / activator protein ( transcription / yeast / zinc - finger protein / glucose repression )

Abstract

The SSN6-TUP1 protein complex represses transcription of diversely regulated genes in the yeast Saccharomyces cerevisiae. Here we present evidence that MIG1, a zinc-finger protein in the EGR1/Zif268 family, recruits SSN6-TUP1 to glucose-repressed promoters. DNA-bound LexA-MIG1 represses transcription of a target gene in glucose-grown cells, and repression… (More)

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