Repression and loss of gene expression outpaces activation and gain in recently duplicated fly genes.

@article{Oakley2006RepressionAL,
  title={Repression and loss of gene expression outpaces activation and gain in recently duplicated fly genes.},
  author={Todd H. Oakley and Bj\orn Ostman and Asa C V Wilson},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2006},
  volume={103 31},
  pages={11637-41}
}
Evolutionists widely acknowledge that regulatory genetic changes are of paramount importance for morphological and genomic evolution. Nevertheless, mechanistic complexity and a paucity of data from nonmodel organisms have prevented testing and quantifying universal hypotheses about the macroevolution of gene regulatory mechanisms. Here, we use a phylogenetic approach to provide a quantitative demonstration of a previously hypothesized trend, whereby the evolutionary rate of repression or loss… CONTINUE READING
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