Representation-mediated Aversion as a Model to Study Psychotic-like States in Mice.

@article{BusquetsGarca2017RepresentationmediatedAA,
  title={Representation-mediated Aversion as a Model to Study Psychotic-like States in Mice.},
  author={Arnau Busquets-Garc{\'i}a and Edgar Soria-G{\'o}mez and G Ferreira and Giovanni Marsicano},
  journal={Bio-protocol},
  year={2017},
  volume={7 12}
}
Several paradigms for rodent models of the cognitive and negative endophenotypes found in schizophrenic patients have been proposed. However, significant efforts are needed in order to study the pathophysiology of schizophrenia-related positive symptoms. Recently, it has been shown that these positive symptoms can be studied in rats by using representation-mediated learning. This learning measure the accuracy of mental representations of reality, also called 'reality testing'. Alterations in… CONTINUE READING

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