• Corpus ID: 12642284

Reporting of Harms Associated with Graded Exercise Therapy and Cognitive Behavioural Therapy in Myalgic Encephalomyelitis / Chronic Fatigue Syndrome

@inproceedings{Kindlon2011ReportingOH,
  title={Reporting of Harms Associated with Graded Exercise Therapy and Cognitive Behavioural Therapy in Myalgic Encephalomyelitis / Chronic Fatigue Syndrome},
  author={Tom Kindlon},
  year={2011}
}
Across different medical fields, authors have placed a greater emphasis on the reporting of efficacy measures than harms in randomised controlled trials (RCTs), particularly of nonpharmacologic interventions. To rectify this situation, the Consolidated Standards of Reporting Trials (CONSORT) group and other researchers have issued guidance to improve the reporting of harms. Graded Exercise Therapy (GET) and Cognitive Behavioural Therapy (CBT) based on increasing activity levels are often… 
Harms and benefits associated with exercise therapy for CFS/ME
  • R. Courtney
  • Psychology, Medicine
    Disability and rehabilitation
  • 2015
TLDR
Based on the inadequacy of existing published data, Kindlon suggests that the possibility of harm after treatment with GET for CFS/ME patients in research studies cannot be ruled out and research into more effective treatments is needed.
Rethinking the Standard of Care for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
TLDR
A pragmatic clinical approach for these often marginalized patients is described, which is likely to be effective at improving fatigue and, to a lesser extent, physical function in ME/CFS but also safe.
Monitoring treatment harm in myalgic encephalomyelitis/chronic fatigue syndrome: A freedom-of-information study of National Health Service specialist centres in England
TLDR
It is recommended that clinics develop standardised protocols for anticipating, recording, and remedying harms, and that these protocols allow for therapies to be discontinued immediately whenever harm is identified.
The PACE Trial Invalidates the Use of Cognitive Behavioral and Graded Exercise Therapy in Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome: A Review
TLDR
The discovery that an increase in exercise tolerance did not lead to a increase in fitness means that an underlying physical problem prevented this; validates that ME/CFS is a physical disease and that none of the treatments studied addressed this issue.
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TLDR
Patients’ symptom responses following these treatments versus pacing therapy are explored, suggesting that cognitive behavioural therapy is of benefit to a small percentage of patients, graded exercise therapy brings about large negative responses in patients and pacing is the most favoured treatment with the lowest negative response rate and the highest reported benefit.
Cognitive behavioural therapy for myalgic encephalomyelitis/chronic fatigue syndrome is not effective. Re-analysis of a Cochrane review
TLDR
Cognitive behavioural therapy should be downgrade to an adjunct support-level therapy, rather than a treatment for chronic fatigue syndrome, because it is not matched by an objective improvement of physical fitness or employment and illness benefit status.
Cognitive-behavior therapy: why is it so vilified in the chronic fatigue syndrome community?
TLDR
This editorial examines the possible factors that have led to the rejection of CBT by many patients and professionals with an interest in CFS and offers some initial thoughts about what might be done to better educate practitioners to help these underserved patients.
Do graded activity therapies cause harm in chronic fatigue syndrome?
  • Tom Kindlon
  • Psychology, Medicine
    Journal of health psychology
  • 2017
TLDR
The trial’s poor results on objective measures of fitness suggest a lack of adherence to the activity component of these therapies, and one cannot conclude that these interventions are safe and risk-free.
Assessment of the scientific rigour of randomized controlled trials on the effectiveness of cognitive behavioural therapy and graded exercise therapy for patients with myalgic encephalomyelitis/chronic fatigue syndrome: A systematic review
TLDR
The methodological quality of studies on the effectiveness of cognitive behavioural therapy and graded exercise therapy was found to be relatively low, as bias was prominently found, affecting the main outcome measures of the studies (fatigue, physical functioning and functional impairment/status).
Treatment of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
TLDR
This meta-analysis excluded from the analysis the studies referenced by Dr. Chu and coworkers and Mr. Kirby about the comparative effectiveness of CBT and GET and predictors of outcomes because they included participants with chronic fatigue rather than ME/CFS.
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