Report of a complex karyotype in recurrent metastatic fibrolamellar hepatocellular carcinoma and a review of hepatocellular carcinoma cytogenetics.

@article{Lowichik1996ReportOA,
  title={Report of a complex karyotype in recurrent metastatic fibrolamellar hepatocellular carcinoma and a review of hepatocellular carcinoma cytogenetics.},
  author={Amy Lowichik and Nancy Rhoda Schneider and Vijay S. Tonk and Mohammad Qasim Ansari and Charles Franklin Timmons},
  journal={Cancer genetics and cytogenetics},
  year={1996},
  volume={88 2},
  pages={
          170-4
        }
}
Metastatic fibrolamellar hepatocellular carcinoma (HCC) was detected in the abdominal lymph nodes of an adolescent male after resection of the primary tumor. No dividing cells were isolated from attempted cytogenetic studies of the primary tumor. However, cytogenetic analysis of lymph node metastases detected 9 and 12 months after partial hepatectomy revealed abnormal hypertriploid karyotypes, with a suggestion of clonal evolution: 62-92 < 3n >,XX, -Y, +3, +6, +6, +7, +7, +8, +10, +13, +15, +16… CONTINUE READING
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Fibrolamellar Carcinoma: 2012 Update

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