Report of a comparative study of DNA damage and repair assays in primary rat hepatocytes with five coded chemicals.

@article{Fautz1991ReportOA,
  title={Report of a comparative study of DNA damage and repair assays in primary rat hepatocytes with five coded chemicals.},
  author={Rolf Fautz and Roy Forster and C M Hechenberger and Thomas Hertner and W von der Hude and Gabriele Kaufmann and H Madle and Stephan Madle and Herbert Georg Miltenburger and Lutz M{\"u}ller},
  journal={Mutation research},
  year={1991},
  volume={260 3},
  pages={281-94}
}
We report the results of a collaborative study for the detection of chemical-induced DNA damage in primary cultures of rat hepatocytes. The methods include the detection of unscheduled DNA synthesis (UDS) with either autoradiography (5 laboratories) or liquid scintillation counting (2 laboratories) and the assessment of DNA single-strand breaks with the… CONTINUE READING